The Bianconeri will try to build on a 5-2 victory at the Stadio Olimpico against Udinese in Rome on Saturday, with AS Roma set to be without key players for the second leg in the capital.
With Andrea Pirlo and Arturo Vidal unavailable due to injury, Juventus coach Massimiliano Allegri will look to play a more attacking style than in the first leg.
With Juve’s second-half display proving a more subdued affair, Roma will be desperate to win on Saturday.
“I’m not sure how to feel, because this will be one of the best games in the history of Juventus,” Allegri said after the match.
“It will be very important to win, and this is our responsibility.
I hope we will be successful.”
Juventus will be without their main attacking threat, Pirlos, as they continue to recover from an ankle injury sustained in the previous round.
However, the Italian champions will be looking to build a three-goal lead on Roma by the time they face off on Saturday night.
Despite the loss of Vidal, Allegri has praised his squad for their work ethic throughout the week.
“They have played well,” he said.
“I’m pleased with our work.
They deserve to be at this level, and we have to work very hard to achieve this.”